Second person in history reportedly cured of HIV

07 March, 2019, 13:00 | Author: Jerome Frank
  • Timothy Brown previously known

Globally, 36.9 million people were living with HIV at the end of 2017, with 59 percent receiving antiretroviral treatment, according the World Health Organization.

The therapy had an early success with Timothy Ray Brown, a US man treated in Germany who is 12 years post-transplant and still free of HIV.

The HIV positive London Patient was given a transplant of stem cells from a donor who had the rare gene mutation CCR5 which is related to HIV resistance.

The London patient, who was being treated for cancer, has now been in remission from HIV for 18 months and is no longer taking HIV drugs.

"The hope is that this will eventually lead to a safe, cost-effective and easy strategy to achieve these results using gene technology or antibody techniques", Pozniak said. Nearly one million people die annually from HIV-related causes.

The man, who has been identified only as the "London patient", was diagnosed with HIV in 2003 and advanced Hodgkin's lymphoma in 2012.

"Two factors are likely at play - the new bone marrow is resistant to HIV and also the new bone marrow is actively eliminating any HIV-infected cells through something called graft versus host disease".

Regular testing has confirmed that the patient's viral load remained undetectable since then. That's key because HIV uses that receptor to gain entry into the cells. Public health experts have a bullish plan to end HIV in the U.S. by 2030, but it does not involve expensive and risky bone-marrow transplants.

Brown, now 52, reportedly lives in Palm Springs, California and is still clear of HIV to this day.

London man becomes second in world to be cured of HIV
London HIV patient becomes world's second AIDS cure hope

This is the second time scientists have done this - the first person cured of AIDS was an American man named Timothy Brown (originally nicknamed "the Berlin patient").

Experts who study AIDS say the success of the Berlin patient and the London patient is very important.

"They used a reduced intense conditioning regimen but I think that had no influence on the outcome", he said. Both required a bone marrow transplant, which allowed physicians to introduce HIV-resistant stem cells into their bodies.

The study also claims that replacing the infected patients' cells with the mutated ones seemed to keep HIV from coming back after the treatment.

The "London patient" case, cautiously reported in the journal Nature as still too "premature" to be declared a cure, comes a decade after Timothy Brown, known in medical circles as the "Berlin patient" was cured by a similar stem cell transplant, galvanizing the field of HIV research and sparking the search for a cure.

Doctors in London say they have apparently eradicated HIV from a patient's body.

The cure for HIV has been invented and medically certified, the President of the United States of America Donald Trump has revealed. Now, tests show he has no sign of the HIV virus in his blood.

"There are actually many strategies right now that are currently being pursued", Henrich said. "Nobody doubted the truth of the report with the Berlin patient, but it was one patient - and which of the many things that were done to him contributed to the apparent cure?" The additional risks of aggressive chemotherapy and possible periods of immune dysfunction also point towards the lower-risk anti-retroviral drugs being a better and cheaper option. "I do have hope".

"I did not want to be the only person in the world cured of HIV", Brown wrote in a medical journal in 2015, explaining why he made a decision to reveal his identity.

Facebook Allows Two-Factor Authentication Phone Number Search
The good news is that while you can't opt out, you can control who can look up your profile using your phone number. Facebook came under heavy fire after admitting that they were using users phone number to directed targeted ads.


  • Freaky  R Kelly interview with Gayle King

    Freaky R Kelly interview with Gayle King

    Parts of Kelly's emotional interview with Gayle King of " CBS This Morning " ran on Tuesday night and Wednesday morning. I didn't do this stuff, this is not me", he shouts, beating his chest, and using several profanities.
    Congress announce new investigation into Donald Trump over potential abuses of power

    Congress announce new investigation into Donald Trump over potential abuses of power

    Strategists said candidates who focus too intently on the findings run the risk of appearing shrill and partisan. Finney brings with her the experience of working directly with Bill Clinton during the Monica Lewinsky scandal.
    Built capsule with a dummy aboard docks at space station

    Built capsule with a dummy aboard docks at space station

    SpaceX's new Crew Dragon capsule has arrived at the International Space Station, acing its second milestone in just over a day. The new space vehicle, carrying only cargo and a human dummy, launched Saturday from NASA's Kennedy Space Center in Florida.
  • Pakistan launches crackdown on militants, detains suspects

    Pakistan launches crackdown on militants, detains suspects

    After failing to adequately convince the FATF, Pakistan is now required to complete actions it has to take by the May timeline. India Wednesday handed over to Pakistan a dossier on "specific details" of involvement of JeM in the attack.
    India 99 for 4, Kohli to Shastri:

    India 99 for 4, Kohli to Shastri: "This is good"

    Australia captain Aaron Finch said his team should have put up a bigger score and stressed on taking regular wickets. I think our quicks looked most effective when they were banging it in, with that came few plays and misses.
    Missing Girls in Humboldt County California

    Missing Girls in Humboldt County California

    A fire captain and firefighter found the girls by following their bootprints, The Associated Press reported . She went looking for them with neighbors and friends before calling the sheriff's office three hours later.
  • Donald Trump Reacts to Democrats Targeting Family Business with Investigations

    Donald Trump Reacts to Democrats Targeting Family Business with Investigations

    Nadler previewed the announcement on ABC's "This Week" on Sunday , contending it's "very clear" that Trump obstructed justice. He said there would be more requests , which might involve additional people.
    The Sunday Edition: President Donald Trump Tweetstorm

    The Sunday Edition: President Donald Trump Tweetstorm

    Jim Jordan, the top Republican on the House Oversight Committee, Cohen's allegations are a distraction from a convicted liar with "zero credibility".
    Donald Trump Kim Jong

    Donald Trump Kim Jong

    White House press secretary Sarah Sanders told reporters that "negotiations are still ongoing" between the two delegations. We had a very successful first summit. " Chairman Kim and myself, we want to do the right deal".
  • Leaving Neverland: Paris Jackson 'still believes dad Michael is innocent'

    Leaving Neverland: Paris Jackson 'still believes dad Michael is innocent'

    Two men, Wade Robson and James Safechuck, say Jackson sexually abused them when they were aged seven and 10. Tiny Record Shop in Toronto has taken a public stand, refusing to stock any of Jackson's records.
    R. Kelly taken back into custody after child-support hearing in Chicago

    R. Kelly taken back into custody after child-support hearing in Chicago

    Kelly denied the allegations in an emotional interview with "CBS This Morning" co-host Gayle King . Kelly has more than 20 people on his staff who, needless to say, are being paid", France said .
    Victor  of record $1.5B lottery drawing comes forward

    Victor of record $1.5B lottery drawing comes forward

    The ticket was purchased October 23, at the KC Mart in Simpsonsville, a town of about 22,000 people outside of Greenville. If it had gone unclaimed, the money would have gone back to the 44 states where the tickets were purchased.


Huawei sues U.S. government over 'unconstitutional' ban
Separately, Huawei's chief financial officer Meng Wanzhou is suing Canada over her arrest at the request of the US. Huawei just upped the ante in its fight with the U.S. over its telecommunication devices.

Canadian Treasury Board Secretary Jane Philpott Resigns Over Scandal
Philpott felt the need to resign as a result of our government's handling of this matter", he said in the release. Former attorney general and justice minister Jody Wilson-Raybould resigned suddenly from Cabinet in February .

Tiger Woods withdraws from Arnold Palmer Invitational because of neck injury
Woods' first appearance at Bay Hill since 2013 generated record crowds and a massive spike in TV ratings. Corey Conners is playing this week on the strength of his early season success.

Samsung developing vertical and external folding phones
The unveiling of the Samsung Galaxy Fold ahead at the Unpacked event earlier this month disrupted the smartphone community. Since the Galaxy S10 5G won't be released for at least a few more months, we don't know how well its camera performs.

India dominates list of world's most polluted cities
The state capital was more polluted than Beijing which used to be the world's most polluted city some years back. A new report by IQAir AirVisual has revealed that 15 of the 20 most polluted cities in the world are in India.

USA merges consulate with Jerusalem embassy, downgrading diplomatic relations with Palestinians
What are they saying? The Palestinian Authority has preemptively rejected the plan, accusing the US of bias toward Israel. A worker hangs a road sign directing to the USA embassy, in the area of the US consulate in Jerusalem , May 7, 2018.

Trump plans to end India's preferential trade treatment
The rules caused severe disruptions for Amazon and Flipkart, which is majority-owned by the United States retail giant Walmart. Trade Representative's Office, the U.S. goods and services trade deficit with India was $27.3 billion in 2017.

Henderson: Derby draw disappointing, but we'll stay positive
Jurgen Klopp reacted angrily to suggestions Liverpool did not take enough risks to beat Everton , insisting "we don't play PlayStation".

India, Pakistan exchange heavy border fire
Cross-border shelling in the past few days has killed seven people on the Pakistani side and four on the Indian side of Kashmir. The United States is "seeking information" on whether Pakistan used U.S. -built F-16 jets to down an Indian warplane, the U.S.

At least 14 dead as storms, possible tornadoes hit Deep South
And he says another radar-confirmed tornado was detected in Henry County, Alabama, moving into a neighboring county. Televised news footage showed smashed buildings with rooftops blown away, cars overturned and debris everywhere.